Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693210 | 0.90 | SLC2A1 (0.59) | SLC2A1MAOBMAOAMAPTSMN1; SMN2 | |
| SCHEMBL10689753 | 0.90 | ALDH1A1 (0.42) | SLC2A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10691903 | 0.86 | MEN1 (0.47) | SLC2A1MAOBMAOAMAPTSMN1; SMN2 | |
| SCHEMBL10693869 | 0.85 | SLC2A1 (0.45) | SLC2A1MAOBMAOAMAPTSMN1; SMN2 | |
| SCHEMBL10689571 | 0.85 | MEN1 (0.51) | SLC2A1MAOBMAOAMAPTSMN1; SMN2 | |
| SCHEMBL10691570 | 0.83 | ALDH1A1 (0.43) | MAPTSMN1; SMN2NPC1RAB9ANOX1 | |
| SCHEMBL7778141 | 0.80 | ALDH1A1 (0.45) | SLC2A1MAOBMAOAMAPTNPC1 | |
| SCHEMBL10689340 | 0.80 | TP53 (0.42) | SLC2A1MAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL10694450 | 0.77 | ALDH1A1 (0.39) | SLC2A1MAPTNPC1LMNAMEN1 | |
| SCHEMBL10690047 | 0.77 | ACACB (0.41) | SLC2A1MAOBMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |