Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 3/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL27794515 | 0.88 | ALDH1A1 (0.48) | ALDH1A1AKR1C3AKR1C2AKR1C1RAB9A | |
| SCHEMBL10691708 | 0.87 | SRD5A2 (0.40) | ALDH1A1AKR1C3AKR1C2AKR1C1RAB9A | |
| SCHEMBL7349547 | 0.81 | MAPT (0.49) | RAB9ANPC1MAPTTDP2HPGD | |
| SCHEMBL9437729 | 0.77 | PTPN1 (0.40) | ALDH1A1MAPTTDP2HPGD | |
| SCHEMBL7348992 | 0.77 | ATM (0.50) | ALDH1A1MAPTATML3MBTL1TDP2 | |
| Benzene SCHEMBL27714049 | 0.76 | MAOA (0.46) | NPC1TDP2SMN1; SMN2 | |
| Carbamic Acid SCHEMBL15477883 | 0.75 | MAOA (0.39) | ALDH1A1AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL7679044 | 0.75 | SMYD3 (0.53) | ALDH1A1AKR1C3AKR1C2AKR1C1ATM | |
| SCHEMBL29408741 | 0.74 | MAOA (0.48) | NPC1NPSR1TDP2SMN1; SMN2 | |
| SCHEMBL6937 | 0.74 | MAOA (0.48) | NPC1NPSR1TDP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |