Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691664 | 0.87 | ALDH1A1 (0.50) | SRD5A2MAPTTDP1ALDH1A1AKR1C3 | |
| SCHEMBL7349547 | 0.80 | MAPT (0.49) | MAPTTDP2HPGDNPC1RAB9A | |
| SCHEMBL7348992 | 0.76 | ATM (0.50) | MAPTALDH1A1TDP2SMN1; SMN2HPGD | |
| SCHEMBL9437729 | 0.76 | PTPN1 (0.40) | MAPTALDH1A1TDP2HPGD | |
| Benzophenone SCHEMBL27794515 | 0.75 | ALDH1A1 (0.48) | SRD5A2AHRMAPTTDP1ALDH1A1 | |
| SCHEMBL10691134 | 0.73 | MAPK1 (0.41) | SRD5A2MAPK1MAPTTDP1ALDH1A1 | |
| SCHEMBL10693566 | 0.73 | SRD5A2 (0.41) | SRD5A2MAPK1MAPTALDH1A1HTT | |
| SCHEMBL11461325 | 0.72 | AHR (0.66) | AHRCMA1 | |
| SCHEMBL3922665 | 0.72 | AHR (0.51) | AHRCMA1MAPTTDP2KMT2A | |
| SCHEMBL10926837 | 0.72 | ESR2 (0.42) | ALDH1A1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |