Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691680 | 0.81 | HPGD (0.47) | HPGDKMT2AMEN1POLB | |
| SCHEMBL10691674 | 0.81 | HPGD (0.47) | HPGDKMT2AMEN1POLB | |
| SCHEMBL10689632 | 0.80 | MTNR1A (0.62) | MTNR1AMTNR1BCCR3HPGDTSHR | |
| SCHEMBL3218987 | 0.77 | HPGD (0.48) | HPGDALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1461837 | 0.74 | ALDH1A1 (0.56) | HPGDALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7574987 | 0.73 | GAA (0.48) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL12194126 | 0.73 | ALOX12 (0.45) | HPGDTSHRBRD4CACNA1GCACNA1H | |
| SCHEMBL10690377 | 0.73 | PPARG (0.50) | MTNR1AMTNR1BALDH1A1KMT2AMAPT | |
| SCHEMBL10684454 | 0.73 | CYP19A1 (0.50) | SIGMAR1 | |
| SCHEMBL7436181 | 0.71 | HPGD (0.62) | CCR3HPGDALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |