Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982940 | 0.79 | IDO1 (0.58) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL27884 | 0.78 | LTA4H (0.81) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL834551 | 0.78 | TAAR1 (0.73) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL1425001 | 0.78 | LTA4H (0.81) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL6880574 | 0.77 | IDO1 (0.57) | IDO1CA12CA1CA2CA7 | |
| 1,4-Dimethoxybenzene SCHEMBL21802643 | 0.76 | CA1 (1.00) | IDO1CA12CA1CA2CA7 | |
| 1,4-Dimethoxybenzene SCHEMBL8489 | 0.76 | CA1 (1.00) | IDO1CA12CA1CA2CA7 | |
| Ammonia Solution, Strong SCHEMBL20919857 | 0.76 | LTA4H (0.77) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL5187124 | 0.76 | CA12 (0.61) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL30878 | 0.76 | CA12 (0.61) | IDO1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1249447-B1 | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol | ALEMBIC LTD (IN) | 2008-10-22 | — | — | EP | claimed |
| US-6756502-B2 | AS CHEMICAL INTERMEDIATE IN PREPARATION OF VENLAFAXINE | ALEMBIC LIMITED (IN) | 2004-06-29 | — | — | US | claimed |
| US-20030195376-A1 | Novel intermediate and processes for its preparation and conversion into a pharmacologically-active agent | ALEMBIC LIMITED (A CORPORATION OF INDIA) (IN) | 2003-10-16 | — | — | US | claimed |
| EP-1249447-A1 | Intermediate for the production of 1-[2-dimethylamino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol | Alembic Limited (IN) | 2002-10-16 | — | — | EP | claimed |
| JP-8225560-A | — | — | None | — | — | JP | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-8283276-B2 | Coordination complex system comprising tautomeric ligands | UNIVERSITEIT VAN AMSTERDAM (NL) | 2012-10-09 | — | — | US | disclosed |
| EP-2220099-B1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | UNIV AMSTERDAM (NL) | 2012-06-27 | — | — | EP | disclosed |
| US-20110003959-A1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | UNIVERSITEIT VAN AMSTERDAM | 2011-01-06 | — | — | US | disclosed |
| EP-2220099-A1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | Universiteit van Amsterdam (NL) | 2010-08-25 | — | — | EP | disclosed |
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2010-05-06 | — | — | US | disclosed |
| US-7709670-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-0850105-A1 | NOVEL CATALYST COMPOSITION | BP Chemicals Limited (GB) | 1998-07-01 | — | — | EP | disclosed |
| US-5731318-A | NEUROLOGICAL DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 1998-03-24 | — | — | US | disclosed |
| WO-1997037765-A1 | NOVEL CATALYST COMPOSITION | BP CHEMICALS LIMITED (GB) | 1997-10-16 | — | — | WO | disclosed |
| US-5607941-A | BENZOMORPHAN DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1997-03-04 | — | — | US | disclosed |
| JP-H08225560-A | NEW AROMATIC DIBENZOFURAN DERIVATIVES AND PHARMACEUTICAL/COSMETIC COMPOSITION CONTAINING THEM | CIRD GALDERMA | 1996-09-03 | — | — | JP | disclosed |
| EP-0521422-B1 | Benzomorphanes and their use as pharmaceuticals | BOEHRINGER INGELHEIM KG (DE) | 1996-05-08 | — | — | EP | disclosed |
| EP-0521422-A1 | Benzomorphanes and their use as pharmaceuticals | BOEHRINGER INGELHEIM KG (DE) | 1993-01-07 | — | — | EP | disclosed |
| US-4012392-A | ANALGESICS, MORPHINE ANTAGONISTS | ACF CHEMIEFARMA N.V. (NL) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003959-A1 | COORDINATION COMPLEX SYSTEM COMPRISING TAUTOMERIC LIGANDS | XRN2, LIG1, H1-2 | IDO1 371/4885CA12 1432/4885CA1 3072/4885 |
| US-20030195376-A1 | Novel intermediate and processes for its preparation and conversion into a pharmacologically-active agent | CYP3A4, CYP4X1, CYP2F1 | IDO1 1241/4885CA12 3185/4885CA1 1679/4885 |
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | OSBP, OSBPL3, OSBP2 | IDO1 2919/4885CA12 1662/4885CA1 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.