Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | CASP1 | P29466 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ANPEP | P15144 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578707 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1TSHR | |
| SCHEMBL10693122 | 0.80 | ADORA2A (0.59) | ALDH1A1MEN1KMT2ANPC1TSHR | |
| SCHEMBL9468786 | 0.79 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2ANPC1TSHR | |
| SCHEMBL4781427 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1TSHR | |
| SCHEMBL19750375 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ANPC1TSHR | |
| SCHEMBL151537 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATSHRCASP1 | |
| SCHEMBL29648925 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATSHRCASP1 | |
| SCHEMBL8995319 | 0.76 | CASP1 (0.86) | ALDH1A1MEN1KMT2ANPC1TSHR | |
| SCHEMBL29045366 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ATSHRCASP1 | |
| SCHEMBL9566650 | 0.75 | CASP1 (0.83) | ALDH1A1MEN1KMT2ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4754024-A | Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups | CIBA-GEIGY CORPORATION | 1988-06-28 | — | — | US | disclosed |
| EP-0112285-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-03-18 | — | — | EP | disclosed |
| EP-0112285-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-06-27 | — | — | EP | disclosed |