Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364095 | 0.80 | HSP90AA1 (0.55) | PTPN1HSP90AA1HSP90AB1MCHR1APP | |
| SCHEMBL16835860 | 0.77 | RAB9A (0.52) | PTPN1HSP90AA1HSP90AB1APPALDH1A1 | |
| SCHEMBL3192555 | 0.76 | ALDH1A1 (0.52) | PTPN1HSP90AA1HSP90AB1MCHR1APP | |
| SCHEMBL10686116 | 0.76 | PTPN1 (0.50) | PTPN1HSP90AA1HSP90AB1ALDH1A1HSD17B10 | |
| SCHEMBL14877433 | 0.76 | BACE1 (0.50) | ALDH1A1ADORA2AKDM4ERAB9AL3MBTL1 | |
| SCHEMBL10754223 | 0.75 | MCHR1 (0.49) | MCHR1ALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL3629826 | 0.74 | ALDH1A1 (0.57) | PTPN1HSP90AA1HSP90AB1APPALDH1A1 | |
| SCHEMBL5682766 | 0.73 | ALDH1A1 (0.59) | HSP90AA1ALDH1A1HSD17B10GAAMETAP2 | |
| SCHEMBL21223648 | 0.73 | APP (0.52) | HSP90AA1HSP90AB1MCHR1APPALDH1A1 | |
| SCHEMBL29746285 | 0.73 | ALDH1A1 (0.59) | HSP90AA1ALDH1A1HSD17B10GAAMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720500-A | N-1,8-naphthyridin-2-yl amides useful as immunostimulants | RHONE-POULENC SANTE (FR) | 1988-01-19 | — | — | US | disclosed |