Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ATP4A | P20648 | 2/20 | 0.38 |
| ▸ | ATP4B | P51164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877433 | 0.79 | BACE1 (0.50) | BACE1L3MBTL1IDO1NPC1RAB9A | |
| SCHEMBL1915309 | 0.78 | ASIC3 (0.53) | PTPN1BACE1HSP90AA1HSP90AB1L3MBTL1 | |
| SCHEMBL30251342 | 0.78 | ASIC3 (0.53) | PTPN1BACE1HSP90AA1HSP90AB1L3MBTL1 | |
| SCHEMBL10691713 | 0.76 | PTPN1 (0.54) | PTPN1HSP90AA1HSP90AB1L3MBTL1RAB9A | |
| SCHEMBL1916434 | 0.74 | HSP90AA1 (0.49) | PTPN1BACE1HSP90AA1HSP90AB1L3MBTL1 | |
| SCHEMBL9375675 | 0.74 | ASIC3 (0.59) | BACE1HSP90AA1NPC1RAB9AMEN1 | |
| SCHEMBL1765925 | 0.72 | BACE1 (0.48) | BACE1KMT2AALDH1A1KDM4ENCF1 | |
| SCHEMBL10691587 | 0.71 | BACE1 (0.50) | BACE1NPC1RAB9AMEN1MAPT | |
| SCHEMBL10689287 | 0.71 | KMO (0.53) | BACE1L3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL6412343 | 0.71 | PIK3CD (0.40) | BACE1IDO1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720500-A | N-1,8-naphthyridin-2-yl amides useful as immunostimulants | RHONE-POULENC SANTE (FR) | 1988-01-19 | — | — | US | disclosed |