(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL23274191

C(=C/c1ccccc1)\c1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.46
CMA1 P23946 1/20 0.45
ALDH1A1 P00352 5/20 0.44
MAPT P10636 4/20 0.44
LMNA P02545 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
RAB9A P51151 2/20 0.44
NFE2L2 Q16236 1/20 0.44
CYP19A1 P11511 1/20 0.44
MAOA P21397 1/20 0.44
JAK2 O60674 1/20 0.44
HTT P42858 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
TRPA1 O75762 1/20 0.44
ALOX5 P09917 1/20 0.44
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL23274192 1.00 MAOB (0.46) MAOBCMA1ALDH1A1MAPTLMNA
Maleic Anhydride SCHEMBL10691759 0.91 MAOB (0.61) MAOBCMA1ALDH1A1MAPTLMNA
Maleic Anhydride SCHEMBL9101172 0.87 LMNA (0.40) MAOBCMA1ALDH1A1MAPTLMNA
Maleic Anhydride SCHEMBL1091519 0.87 LMNA (0.40) MAOBCMA1ALDH1A1MAPTLMNA
Maleic Anhydride SCHEMBL2328932 0.85 ALDH1A1 (0.36) MAOBCMA1ALDH1A1MAPTLMNA
Maleic Anhydride SCHEMBL5884683 0.82 PPARG (0.43) ALDH1A1MAPTLMNAKMT2ANFE2L2
Styrene SCHEMBL16058 0.82 ALDH1A1 (0.61) CMA1ALDH1A1MAPTLMNAMEN1
Styrene SCHEMBL10541015 0.82 ALDH1A1 (0.61) CMA1ALDH1A1MAPTLMNAMEN1
Styrene SCHEMBL28478709 0.82 ALDH1A1 (0.61) CMA1ALDH1A1MAPTLMNAMEN1
Styrene SCHEMBL22656704 0.80 ALDH1A1 (0.58) CMA1ALDH1A1MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629341-B2 Functional derivatives of maleimide copolymers for nanodisc production THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2026-05-19 US disclosed
US-20220347114-A1 FUNCTIONAL DERIVATIVES OF MALEIMIDE COPOLYMERS FOR NANODISC PRODUCTION THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2022-11-03 US disclosed
EP-4049035-A1 FUNCTIONAL DERIVATIVES OF MALEIMIDE COPOLYMERS FOR NANODISC PRODUCTION The Governors Of The University Of Alberta (CA) 2022-08-31 EP disclosed
WO-2021081329-A1 FUNCTIONAL DERIVATIVES OF MALEIMIDE COPOLYMERS FOR NANODISC PRODUCTION THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2021-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220347114-A1 FUNCTIONAL DERIVATIVES OF MALEIMIDE COPOLYMERS FOR NANODISC PRODUCTION MLEC, PHOSPHO1, PEBP1 MAOB 4470/4885CMA1 4823/4885ALDH1A1 4196/4885
US-12629341-B2 Functional derivatives of maleimide copolymers for nanodisc production PHOSPHO1, HACD3, C3AR1 MAOB 2374/4885CMA1 1353/4885ALDH1A1 1732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.