Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8164591 | 0.84 | HSD17B10 (0.45) | HSD17B10KDM4EALDH1A1POLBGAA | |
| Hydrochloric Acid SCHEMBL9812898 | 0.82 | HSD17B10 (0.44) | HSD17B10KDM4EALDH1A1POLBGAA | |
| SCHEMBL9414558 | 0.81 | MAPT (0.41) | HSD17B10KDM4EALDH1A1GAAMAPT | |
| SCHEMBL9138757 | 0.79 | HSD17B10 (0.39) | HSD17B10KDM4EALDH1A1POLBGAA | |
| SCHEMBL10581528 | 0.78 | CA2 (0.43) | HSD17B10KDM4EALDH1A1POLBGAA | |
| SCHEMBL10477944 | 0.77 | HSD17B10 (0.44) | HSD17B10KDM4EALDH1A1POLBGAA | |
| SCHEMBL10691812 | 0.76 | HSD17B10 (0.37) | HSD17B10KDM4EALDH1A1POLBGAA | |
| SCHEMBL10696544 | 0.75 | RAPGEF4 (0.36) | HSD17B10KDM4EALDH1A1POLBGAA | |
| SCHEMBL11670686 | 0.74 | HSD17B10 (0.51) | HSD17B10KDM4EALDH1A1POLBGAA | |
| SCHEMBL10884624 | 0.73 | ALDH1A1 (0.56) | HSD17B10KDM4EALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |