Dimethylamine

Dimethylamine

SCHEMBL10691829

CNC.O=S(=O)(CCO)c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.55
PSIP1 O75475 1/20 0.54
HSD11B1 P28845 4/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HDAC1 Q13547 3/20 0.47
MAPT P10636 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
POLB P06746 1/20 0.46
HTT P42858 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2454945 0.92 CA2 (0.63) CA2PSIP1HSD11B1L3MBTL1HDAC1
Diethylamine SCHEMBL10690280 0.87 PSIP1 (0.53) CA2PSIP1HSD11B1L3MBTL1HDAC1
SCHEMBL5664467 0.84 CA2 (0.60) CA2PSIP1HSD11B1L3MBTL1HDAC1
SCHEMBL9325260 0.80 CA2 (0.78) CA2MAPTPOLBHTTALDH1A1
SCHEMBL7207184 0.79 CA2 (0.66) CA2PSIP1HSD11B1L3MBTL1HDAC1
SCHEMBL7295504 0.78 CA2 (0.58) CA2MAPTPOLBALDH1A1TP53
SCHEMBL777601 0.78 PSIP1 (0.67) CA2PSIP1HSD11B1L3MBTL1HDAC1
SCHEMBL3917294 0.78 CA2 (0.67) CA2PSIP1HSD11B1L3MBTL1HDAC1
SCHEMBL552911 0.78 L3MBTL1 (0.56) PSIP1HSD11B1L3MBTL1HDAC1MAPT
SCHEMBL23877095 0.77 L3MBTL1 (0.56) CA2PSIP1HSD11B1L3MBTL1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed