Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GLS | O94925 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994436 | 0.85 | ALDH1A1 (0.51) | ALDH1A1CYP3A4TSHRGLSCASP3 | |
| SCHEMBL13649427 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TSHRGLSCASP3 | |
| SCHEMBL10991745 | 0.80 | TSHR (0.49) | ALDH1A1CYP3A4TSHRGLSCASP3 | |
| SCHEMBL10692775 | 0.79 | TSHR (0.61) | ALDH1A1CYP3A4TSHRGLSCASP3 | |
| SCHEMBL10692455 | 0.79 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TSHRGLSCASP3 | |
| SCHEMBL20852439 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10694568 | 0.77 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TSHRGLSCASP3 | |
| SCHEMBL28833055 | 0.77 | CTSD (0.47) | ALDH1A1CYP3A4TSHRSMN1; SMN2MAPT | |
| SCHEMBL10299137 | 0.77 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRGLSCASP3 | |
| SCHEMBL1286155 | 0.77 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRGLSCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |