Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GLS | O94925 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994436 | 0.83 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4GLSSMN1; SMN2 | |
| SCHEMBL10691888 | 0.80 | ALDH1A1 (0.57) | TSHRALDH1A1CYP3A4GLSSMN1; SMN2 | |
| SCHEMBL10694568 | 0.77 | ALDH1A1 (0.57) | TSHRALDH1A1CYP3A4GLSSMN1; SMN2 | |
| SCHEMBL13649427 | 0.75 | ALDH1A1 (0.62) | TSHRALDH1A1CYP3A4GLSSMN1; SMN2 | |
| SCHEMBL10988657 | 0.73 | CYP3A4 (0.53) | TSHRALDH1A1CYP3A4GLSSMN1; SMN2 | |
| SCHEMBL10692775 | 0.72 | TSHR (0.61) | TSHRALDH1A1CYP3A4GLSSMN1; SMN2 | |
| SCHEMBL10692455 | 0.72 | ALDH1A1 (0.58) | TSHRALDH1A1CYP3A4GLSSMN1; SMN2 | |
| SCHEMBL4158526 | 0.71 | PKM (0.62) | TSHRALDH1A1CYP3A4GLSUSP2 | |
| SCHEMBL4162007 | 0.71 | PKM (0.62) | TSHRALDH1A1CYP3A4GLSUSP2 | |
| SCHEMBL4158522 | 0.71 | PKM (0.62) | TSHRALDH1A1CYP3A4GLSUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |