SCHEMBL10691905

SCHEMBL10691905

ClCCCOc1c2ccccc2cc2cc(Cl)ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
CYP2A6 P11509 1/20 0.40
MCL1 Q07820 6/20 0.36
BCL2 P10415 2/20 0.36
BCL2L1 Q07817 2/20 0.36
BAD Q92934 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
HTR1B P28222 1/20 0.35
AHR P35869 1/20 0.34
HTR2A P28223 1/20 0.33
KCNA3 P22001 1/20 0.33
KCNA5 P22460 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695347 0.89 HTR1B (0.47) L3MBTL1CYP2A6MCL1BCL2BCL2L1
SCHEMBL10692520 0.88 L3MBTL1 (0.50) L3MBTL1GPR84HTR1BAHRHTR2A
SCHEMBL10692715 0.86 L3MBTL1 (0.40) L3MBTL1CYP2A6MCL1BCL2BCL2L1
SCHEMBL10692973 0.85 S1PR4 (0.34) CYP2A6GPR84KCNA3KCNA5CYP1A2
SCHEMBL10693069 0.83 L3MBTL1 (0.48) L3MBTL1GPR84HTR1BAHRHTR2A
SCHEMBL10693502 0.82 L3MBTL1 (0.47) L3MBTL1GPR84HTR1BAHRHTR2A
SCHEMBL10692840 0.82 L3MBTL1 (0.47) L3MBTL1GPR84HTR1BAHRHTR2A
SCHEMBL10694532 0.82 L3MBTL1 (0.47) L3MBTL1GPR84HTR1BAHRHTR2A
SCHEMBL10693825 0.82 L3MBTL1 (0.47) L3MBTL1GPR84HTR1BAHRHTR2A
SCHEMBL10691921 0.82 L3MBTL1 (0.47) L3MBTL1GPR84HTR1BAHRHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4792551-A 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents SYNTEX (U.S.A.) INC. (US) 1988-12-20 US disclosed
EP-0132351-A2 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1985-01-30 EP disclosed