SCHEMBL10692973

SCHEMBL10692973

ClCCOc1c2ccc(Cl)cc2cc2cc(Cl)ccc12

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 4/20 0.34
CYP2A6 P11509 1/20 0.33
KCNA3 P22001 2/20 0.33
KCNA5 P22460 1/20 0.33
CYP1A2 P05177 1/20 0.30
POLB P06746 2/20 0.30
NR4A2 P43354 1/20 0.30
SOS2 Q07890 1/20 0.30
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10691905 0.85 L3MBTL1 (0.41) CYP2A6KCNA3KCNA5CYP1A2POLB
SCHEMBL10694803 0.84 PARP1 (0.42)
SCHEMBL11172258 0.80 ABCB11 (0.38) CYP2A6KCNA3KCNA5
SCHEMBL10692528 0.80 MAPT (0.49) CYP1A2NR4A2GAA
SCHEMBL10695347 0.77 HTR1B (0.47) CYP2A6GPR84
SCHEMBL10694110 0.77 L3MBTL1 (0.50) KCNA3CYP1A2GPR84
SCHEMBL10693121 0.77 NCEH1 (0.33) S1PR4KCNA3KCNA5POLB
SCHEMBL10691402 0.76 LMNA (0.54) CYP1A2POLBGAATSHR
SCHEMBL10692715 0.74 L3MBTL1 (0.40) CYP2A6KCNA3KCNA5CYP1A2NR4A2
SCHEMBL10692349 0.72 HPGD (0.48) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4792551-A 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents SYNTEX (U.S.A.) INC. (US) 1988-12-20 US disclosed
EP-0132351-A2 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1985-01-30 EP disclosed