Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698208 | 0.91 | CYP2C9 (0.62) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL14392906 | 0.82 | CYP2C9 (0.71) | CYP2C9ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4766529 | 0.81 | CA12 (0.61) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL10692230 | 0.78 | ALDH1A1 (0.65) | CYP2C9ALDH1A1NPSR1LMNAKDM4E | |
| SCHEMBL14508938 | 0.78 | CYP2C9 (0.60) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL6291291 | 0.78 | ALDH1A1 (0.46) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL10738787 | 0.77 | MEN1 (0.62) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL10894414 | 0.77 | LMNA (0.53) | ALDH1A1NPSR1LMNAMEN1KMT2A | |
| SCHEMBL14101774 | 0.75 | CYP2C9 (0.64) | CYP2C9ALDH1A1NPSR1LMNAMEN1 | |
| SCHEMBL2011715 | 0.74 | GAA (0.55) | ALDH1A1LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721809-A | Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-26 | — | — | US | claimed |
| EP-0260901-A1 | Benzenesulphonamides useful as anti-arrythmic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4721809-A | Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |