Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694255 | 0.83 | ALDH1A1 (0.59) | ALDH1A1CYP2C9NPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL9836671 | 0.82 | SIGMAR1 (0.68) | ALDH1A1CYP2C9SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL9698208 | 0.81 | CYP2C9 (0.62) | ALDH1A1CYP2C9NPSR1SMN1; SMN2MAPT | |
| SCHEMBL10679386 | 0.80 | ALDH1A1 (0.70) | ALDH1A1NPSR1TSHRCA12CA1 | |
| SCHEMBL10774775 | 0.80 | POLB (0.73) | ALDH1A1NPSR1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL10694347 | 0.80 | ALDH1A1 (0.69) | ALDH1A1NPSR1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL10691913 | 0.78 | CYP2C9 (0.59) | ALDH1A1CYP2C9NPSR1SMN1; SMN2MAPT | |
| SCHEMBL14392906 | 0.77 | CYP2C9 (0.71) | ALDH1A1CYP2C9SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL9834718 | 0.77 | RORC (0.46) | ALDH1A1CYP2C9NPSR1SMN1; SMN2MAPT | |
| SCHEMBL10683290 | 0.77 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721809-A | Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-26 | — | — | US | claimed |
| EP-0260901-A1 | Benzenesulphonamides useful as anti-arrythmic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4721809-A | Alkylsulfonamido or perfluoroalkylsulfonamido benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |