Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693157 | 0.89 | LMNA (0.44) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL339072 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL337709 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL10680094 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| Dimethylamine SCHEMBL8359926 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL11281281 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL10599114 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL11063311 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL339729 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL1653589 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |