Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692102 | 0.90 | LMNA (0.44) | LMNAPDE4DALDH1A1NR3C1MAPT | |
| SCHEMBL10691917 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL11070301 | 0.84 | ATM (0.48) | LMNAPDE4DALDH1A1KDM4EMEN1 | |
| SCHEMBL4686888 | 0.79 | ALDH1A1 (0.58) | LMNAALDH1A1KDM4EMEN1GAA | |
| SCHEMBL11543103 | 0.79 | ALDH1A1 (0.67) | LMNAALDH1A1NR3C1MAPTHPGD | |
| SCHEMBL339072 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL10693119 | 0.76 | ALDH1A1 (0.46) | LMNAALDH1A1KDM4EMEN1GAA | |
| SCHEMBL337709 | 0.76 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1GAAKMT2A | |
| SCHEMBL10693011 | 0.74 | CDK1 (0.50) | PDE4DALDH1A1KDM4EGAANR3C1 | |
| SCHEMBL11068781 | 0.74 | ATM (0.43) | ALDH1A1KDM4EMAPTHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |