Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RBP4 | P02753 | 5/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621470 | 0.93 | RBP4 (0.52) | MAPTRBP4HRH4NOTUMMAPK1 | |
| SCHEMBL10678967 | 0.92 | RBP4 (0.51) | MAPTRBP4HRH4MAPK1HTT | |
| Fumaric Acid SCHEMBL10623505 | 0.87 | HTR1A (0.47) | MAPTRBP4HRH4MAPK1TAS1R3 | |
| Maleic Acid SCHEMBL10623496 | 0.87 | HTR1A (0.47) | MAPTRBP4HRH4MAPK1TAS1R3 | |
| Fumaric Acid SCHEMBL10621423 | 0.86 | HTR1A (0.46) | MAPTRBP4MAPK1HTTTAS1R3 | |
| Maleic Acid SCHEMBL10621414 | 0.86 | HTR1A (0.46) | MAPTRBP4MAPK1HTTTAS1R3 | |
| SCHEMBL10621469 | 0.83 | KDM4E (0.43) | MAPTHRH4KMT2ASRD5A1TDP1 | |
| SCHEMBL10623647 | 0.80 | RAB9A (0.44) | MAPTNOTUMMEN1KMT2ASRD5A1 | |
| SCHEMBL10624542 | 0.79 | KDM4E (0.50) | MAPTMAPK1SRD5A1TDP1TSHR | |
| SCHEMBL10624196 | 0.79 | RAB9A (0.54) | MAPTMAPK1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4723007-A | ANALGESICS, ANTIPSYCHOTIC AGENTS; INTERMEDIATES FOR PROCESSING | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-02-02 | — | — | US | claimed |