Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPN | P05981 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30177232 | 0.86 | MAOA (0.61) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL4652610 | 0.86 | MAOA (0.61) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL7938898 | 0.85 | TSHR (0.43) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL15771707 | 0.82 | CYP1A2 (0.54) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL22133468 | 0.77 | GRIA1 (0.39) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL599052 | 0.76 | MAOA (0.46) | KMT2AMEN1TDP1MAPTALDH1A1 | |
| SCHEMBL2331538 | 0.75 | GRIA1 (0.38) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL13839572 | 0.74 | KMT2A (0.41) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL21730835 | 0.74 | TDP2 (0.46) | KMT2AMEN1TDP1MAPTUSP2 | |
| SCHEMBL20886849 | 0.74 | TDP2 (0.64) | MAPTGRIA1CACNG8TDP2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |