SCHEMBL599052

SCHEMBL599052

Cc1cccc2c1-c1ccccc1C2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.46
HTR2B P41595 1/20 0.46
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 1/20 0.42
KMT2A Q03164 2/20 0.42
CASP3 P42574 1/20 0.42
CASP6 P55212 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HTR1A P08908 2/20 0.41
DRD2 P14416 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4652610 0.84 MAOA (0.61) MAOAHTR2BALDH1A1KDM4ENPC1
SCHEMBL30177232 0.84 MAOA (0.61) MAOAHTR2BALDH1A1KDM4ENPC1
SCHEMBL7938898 0.84 TSHR (0.43) ALDH1A1MAPTHPGDSMN1; SMN2KMT2A
Fluorene SCHEMBL28561231 0.81 MAOA (0.54) MAOAHTR2BALDH1A1KDM4ENPC1
SCHEMBL30753839 0.81 ALDH1A1 (0.43) MAOAHTR2BALDH1A1KDM4EMAPT
SCHEMBL21694429 0.80 MAPT (0.45) ALDH1A1KDM4ENPC1LMNAMAPT
SCHEMBL22889028 0.80 METAP1 (0.43) ALDH1A1KDM4ENPC1LMNAMAPT
Fluorene SCHEMBL18316006 0.80 MAOA (0.48) MAOAHTR2BALDH1A1KDM4ENPC1
SCHEMBL30403300 0.79 MAOA (0.56) MAOAHTR2BALDH1A1KDM4ENPC1
SCHEMBL2048985 0.78 ALDH1A1 (0.48) MAOAHTR2BALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115792174-A Method for dividing hydrocarbon source rock deposition organic phase by using dibenzofuran and methylfluorene 中国石油化工股份有限公司 2023-03-14 CN claimed
US-6262197-B1 AS POLYMERIZATION CATALYST IN OLEFIN POLYMERIZATION TARGOR GMBH (DE) 2001-07-17 US claimed
EP-0627440-A1 9-Substituted fluorenyl compounds and the preparation and use of metallocenes thereof PHILLIPS PETROLEUM COMPANY (US) 1994-12-07 EP claimed
US-5210352-A Fluorene compounds PHILLIPS PETROLEUM COMPANY (US) 1993-05-11 US claimed
CN-119371298-A Method for efficiently synthesizing indenone compound 南阳师范学院 2025-01-28 CN disclosed
CN-118955428-A Benzothiazinone vinylidene indene series compound with dibenzothiazepine octacycle system structure and preparation method thereof 浙大城市学院 2024-11-15 CN disclosed
CN-118302504-A Preparation of renewable jet fuel from catalytic pyrolysis feedstock IFP 新能源公司 2024-07-05 CN disclosed
CN-118265764-A Preparation of renewable diesel from catalytic pyrolysis feedstock IFP 新能源公司 2024-06-28 CN disclosed
CN-115792174-A Method for dividing hydrocarbon source rock deposition organic phase by using dibenzofuran and methylfluorene 中国石油化工股份有限公司 2023-03-14 CN disclosed
CN-110691820-B Reinforced polycarbonate resin composition 帝人株式会社 2022-03-18 CN disclosed
US-20220059775-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-02-24 US disclosed
CN-112105654-A Curable resin mixture, curable resin composition, and cured product thereof 日本化药株式会社 2020-12-18 CN disclosed
US-5182316-A Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-26 US disclosed
CN-1066440-A Cyclopeutadiene type compounds and preparation method thereof PHILLIPS PETROLEUM CO (US) 1992-11-25 CN disclosed
EP-0512554-A2 Cyclopetadiene type compounds and method for making PHILLIPS PETROLEUM COMPANY (US) 1992-11-11 EP disclosed
US-5118559-A Dibenzofulvene compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US disclosed
US-5079260-A Side effect reduction; fluorene derivatives NOVA PHARMACEUTICAL CORPORATION (US) 1992-01-07 US disclosed
WO-1991018596-A1 METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN WEITZBERG MOSHE (US) 1991-12-12 WO disclosed
US-5047444-A Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-10 US disclosed
EP-0400972-A2 Fluorescent degree of cure monitors MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP disclosed