Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305877 | 0.78 | HCRTR1 (0.54) | HCRTR1HSD17B10KDM4EHCRTR2LMNA | |
| SCHEMBL10381438 | 0.78 | HCRTR1 (0.61) | HCRTR1HCRTR2LMNAMAPTGAA | |
| SCHEMBL530230 | 0.77 | TSHR (0.63) | HCRTR1HSD17B10KDM4EHCRTR2LMNA | |
| Water SCHEMBL9316910 | 0.75 | ALDH1A1 (0.62) | HCRTR1HSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL10381433 | 0.75 | TP53 (0.69) | HCRTR1HCRTR2LMNAMAPTGAA | |
| SCHEMBL12536449 | 0.75 | MAPT (0.57) | HCRTR1HSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL6969031 | 0.75 | HCRTR1 (0.66) | HCRTR1HSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL206583 | 0.75 | HCRTR1 (0.66) | HCRTR1HSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL11763044 | 0.75 | HCRTR1 (0.66) | HCRTR1HSD17B10KDM4ELMNAALDH1A1 | |
| SCHEMBL5322417 | 0.74 | LMNA (0.51) | HCRTR1HSD17B10KDM4EHCRTR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253501-A2 | N-disubstituted cycloalkylmethyl amines useful as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |