Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.62 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.62 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | GCGR | P47871 | 4/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692180 | 0.89 | RAB9A (0.71) | KMT2APRKAG1PRKAB1PRKAA2RAB9A | |
| SCHEMBL10691975 | 0.84 | CYP1A2 (0.59) | KMT2APRKAG1PRKAB1PRKAA2PTPN1 | |
| SCHEMBL11118850 | 0.83 | MAPT (0.58) | KMT2APRKAG1PRKAB1PRKAA2RAB9A | |
| SCHEMBL10360138 | 0.83 | PRKAG1 (0.49) | KMT2APRKAG1PRKAB1PRKAA2RAB9A | |
| SCHEMBL14959209 | 0.83 | KMT2A (0.65) | KMT2APRKAG1PRKAB1PRKAA2RAB9A | |
| SCHEMBL16208396 | 0.80 | PTPN1 (0.59) | KMT2APTPN1ALDH1A1HPGDTDP1 | |
| SCHEMBL11119849 | 0.80 | KMT2A (0.60) | KMT2APRKAG1PRKAB1PRKAA2RAB9A | |
| SCHEMBL15678761 | 0.80 | KMT2A (0.60) | KMT2APRKAG1PRKAB1PRKAA2RAB9A | |
| SCHEMBL12387288 | 0.79 | PRKAG1 (0.81) | KMT2APRKAG1PRKAB1PRKAA2RAB9A | |
| SCHEMBL3515244 | 0.79 | KMT2A (1.00) | KMT2ARAB9AHSD17B10GCGRALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |
| EP-0128862-A2 | Anti-corrosive coating composition | CIBA-GEIGY AG (CH) | 1984-12-19 | — | — | EP | disclosed |