Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609318 | 0.81 | OPRK1 (0.60) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL5317697 | 0.78 | LMNA (0.52) | LMNAADRA1ADRD3HTR1AADRA2A | |
| SCHEMBL5682627 | 0.75 | OPRM1 (0.46) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL2978589 | 0.75 | LMNA (0.66) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL31094667 | 0.75 | LMNA (0.66) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL12610310 | 0.75 | LMNA (0.66) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL9722026 | 0.74 | HIF1A (0.55) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL10206558 | 0.74 | HIF1A (0.55) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL1132949 | 0.74 | OPRK1 (0.53) | HIF1ALMNAGALR3ADRB1ADRA1A | |
| SCHEMBL13310383 | 0.73 | OPRM1 (0.54) | HIF1ALMNAGALR3ADRB1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734376-A | SELECTIVE EXTRACTION AND COLORMETRIC DETERMINATION | THE PRESIDENT & TRUSTEES OF THE MIAMI UNIVERSITY (US) | 1988-03-29 | — | — | US | disclosed |
| US-4659815-A | Chromogenic aza-12-crown-4 ethers and method of using same for the detection of lithium | THE PRESIDENT AND TRUSTEES OF THE MIAMI UNIVERSITY (US) | 1987-04-21 | — | — | US | disclosed |