Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066802 | 0.76 | KMT2A (0.48) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL14363762 | 0.76 | GLA (0.31) | MGLLPOLB | |
| SCHEMBL669626 | 0.75 | KMT2A (0.54) | KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL28771494 | 0.75 | KMT2A (0.47) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL9608993 | 0.74 | BCHE (0.53) | KMT2ALMNAMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL19309377 | 0.74 | KMT2A (0.53) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL133554 | 0.74 | KMT2A (0.53) | KMT2AF2LMNAMAPK1TSHR | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.73 | LMNA (0.70) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL52413 | 0.73 | LMNA (0.70) | KMT2AF2LMNAMAPK1TSHR | |
| Benzene SCHEMBL27793442 | 0.73 | LMNA (0.70) | KMT2AF2LMNAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023030385-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-03-09 | — | — | WO | disclosed |