SCHEMBL133554

SCHEMBL133554

O=C(ON1C(=O)CCC1=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.53
MGLL Q99685 1/20 0.50
F2 P00734 1/20 0.48
LMNA P02545 1/20 0.48
PARL Q9H300 2/20 0.46
TSHR P16473 3/20 0.45
MAPK1 P28482 2/20 0.45
MAPT P10636 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX12 P18054 1/20 0.41
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19309377 1.00 KMT2A (0.53) KMT2AMGLLF2LMNAPARL
SCHEMBL15169077 0.93 KMT2A (0.48) KMT2AMGLLF2LMNAPARL
SCHEMBL76714 0.93 KMT2A (0.48) KMT2AMGLLF2LMNAPARL
SCHEMBL15169078 0.93 KMT2A (0.48) KMT2AMGLLF2LMNAPARL
SCHEMBL300884 0.90 CA12 (0.42) KMT2AMGLLLMNAPARLMAPK1
SCHEMBL4872950 0.90 SMN1; SMN2 (0.54) KMT2AMGLLPARLMAPK1MAPT
SCHEMBL660306 0.89 MGLL (0.46) KMT2AMGLLF2LMNAPARL
SCHEMBL20027226 0.88 KMT2A (0.47) KMT2AMGLLF2LMNAPARL
SCHEMBL27717830 0.87 CA1 (0.55) KMT2AMGLLTSHRMAPTSMN1; SMN2
SCHEMBL14860981 0.87 MAPK1 (0.48) KMT2AMGLLLMNAPARLTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025046227-A1 X-RAY VISIBLE IMPLANTABLE SCAFFOLDS UCL BUSINESS LTD (GB) 2025-03-06 WO claimed
CN-119192465-A Preparation method and application of polymer-gadolinium hybrid contrast agent 青岛科技大学 2024-12-27 CN claimed
CN-118185029-A Self-repairable modified polyglutamic acid bionic polymer brush lubricant and preparation method and application thereof 华东理工大学 2024-06-14 CN claimed
CN-117599211-A Tumor-targeted drug delivery system and preparation method and application thereof 河南省肿瘤医院 2024-02-27 CN claimed
CN-117414434-A Targeted tumor carrier based on milk extracellular vesicles, and preparation method and application thereof 河南省肿瘤医院 2024-01-19 CN claimed
CN-117074583-A Rapid preparation and detection method for grease sample based on support liquid phase extraction and in-situ derivatization 郑州大学 2023-11-17 CN claimed
CN-116407670-A Absorbable medical soft tissue adhesive and preparation method and application thereof 中国科学院长春应用化学研究所 2023-07-11 CN claimed
CN-116407668-A Quick-curing and degradable strong bone adhesive and preparation method thereof 中国科学院长春应用化学研究所 2023-07-11 CN claimed
CN-116068167-A Separation and detection method of extracellular biomacromolecule 厦门福流生物科技有限公司 2023-05-05 CN claimed
CN-112142823-B ZP-1609 synthesis method 深圳翰宇药业股份有限公司 2022-08-05 CN claimed
CN-102964598-A Polymaleimide polymer as well as preparation method and application of polymaleimide polymer CAS GUANGZHOU CHEMISTRY CO LTD 2013-03-13 CN claimed
US-12625144-B2 Chemoselective sensitivity booster for tagging a peptide, peptide conjugate, or similar reactive molecule Indian Institute Of Science Education And Research Bhopal (IN) 2026-05-12 US disclosed
WO-2026089540-A1 EFFICIENT TARGET PROTEIN-SPECIFIC LIGAND SELECTION METHOD USING APTAMER 전북대학교산학협력단 2026-04-30 WO disclosed
US-20250375542-A1 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS CANCER TARGETED TECH LLC (US) 2025-12-11 US disclosed
EP-4658744-A1 AUTOMATIC DISHWASHING COMPOSITION COMPRISING A STRUCTURAL POLYPEPTIDE AMSilk GmbH (DE) 2025-12-10 EP disclosed
US-4083793-A ETHYLENE OXIDE FATTY ALCOHOL ADDUCT, POLYOXYETHYLENE GLYCOL MODIFIED WITH FATTY ALCOHOL, SODIUM SOAP, SODIUM ALKYLBENZENESULFONATE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) 1978-04-11 US disclosed
US-4003841-A Coated stabilized bleach activators, process and washing compositions HENKEL & CIE G.M.B.H. (DT) 1977-01-18 US disclosed
US-3975280-A Storage-stable, readily-soluble detergent additives, coating compositions and process HENKEL & CIE G.M.B.H. (DT) 1976-08-17 US disclosed
US-3965024-A Washing agent compositions and washing assistant composition containing phosphonopolycarboxylate sequestering agents HENKEL & CIE G.M.B.H. (DT) 1976-06-22 US disclosed
US-3943178-A WASHING AGENT HENKEL & CIE GMBH (DT) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625144-B2 Chemoselective sensitivity booster for tagging a peptide, peptide conjugate, or similar reactive molecule DPYSL3, CD2BP2, PTMS KMT2A 4121/4885MGLL 4591/4885F2 3596/4885
US-20250375542-A1 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS FOLH1, PSMA1, PSMA2 KMT2A 1950/4885MGLL 2244/4885F2 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.