Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.39 |
| ▸ | GRK2 | P25098 | 5/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693756 | 0.84 | AAK1 (0.42) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL10687930 | 0.84 | ROCK2 (0.41) | HSD17B10GAAROCK2GRK2KLK1 | |
| Hydrochloric Acid SCHEMBL10695809 | 0.83 | AAK1 (0.41) | NPC1MAPTRAB9AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10690068 | 0.80 | KDM4E (0.38) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL2899660 | 0.78 | DDAH1 (0.55) | MAPTALDH1A1GAASMN1; SMN2CHEK1 | |
| SCHEMBL10692342 | 0.78 | NPC1 (0.37) | NPC1MAPTRAB9AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10689236 | 0.77 | NPC1 (0.36) | NPC1MAPTRAB9AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10692572 | 0.75 | WNT1 (0.47) | GAAHDAC1MGAMSIMGAM2 | |
| SCHEMBL10693217 | 0.75 | CYP1A2 (0.40) | NPC1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL4454948 | 0.75 | KLK1 (0.63) | NPC1MAPTRAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252507-A1 | 2-(4-Pyridylaminomethyl)-benzimidazole derivatives having antiviral activity | Maruishi Seiyaku Kabushiki Kaisha (JP) | 1988-01-13 | — | — | EP | claimed |