Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142699 | 0.89 | KDM4E (0.60) | MAOAMAOBKDM4EHTTRAB9A | |
| SCHEMBL9886094 | 0.83 | MAOA (0.59) | MAOAMAOBKDM4EHTTRAB9A | |
| SCHEMBL14391568 | 0.81 | MAOA (0.58) | MAOAMAOBKDM4EHTTRAB9A | |
| SCHEMBL2769931 | 0.80 | MAOA (0.51) | MAOAMAOBKDM4EHTTRAB9A | |
| Hydrochloric Acid SCHEMBL637296 | 0.80 | MAOA (0.56) | MAOAMAOBKDM4EHTTRAB9A | |
| SCHEMBL10645040 | 0.80 | MTNR1A (0.56) | MAOAMAOBPDE4APDE4BPDE4C | |
| SCHEMBL637660 | 0.80 | HTT (0.51) | MAOAMAOBKDM4EHTTRAB9A | |
| SCHEMBL1506959 | 0.78 | HTR1A (0.53) | MAOAMAOBKDM4EHTTNPC1 | |
| SCHEMBL10641796 | 0.78 | MAOA (0.57) | MAOAMAOBKDM4EHTTRAB9A | |
| SCHEMBL15854518 | 0.78 | KDM4E (0.77) | MAOAMAOBKDM4EHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792559-A | 1,2,3,4-tetrahydroquinoline substituted 5-aminopentanenitrile compounds and their use as calcium modulators | ADIR ET COMPAGNIE (FR) | 1988-12-20 | — | — | US | disclosed |