Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127615 | 0.79 | MEN1 (0.58) | MEN1KMT2AELANEALDH1A1L3MBTL1 | |
| SCHEMBL29754212 | 0.79 | MEN1 (0.58) | MEN1KMT2AELANEALDH1A1L3MBTL1 | |
| Butane SCHEMBL7228806 | 0.76 | TDP1 (0.46) | MEN1KMT2AALDH1A1GAALMNA | |
| Hexane SCHEMBL27689826 | 0.75 | ALDH1A1 (0.42) | MEN1KMT2AERN1ALDH1A1GAA | |
| Pyrene SCHEMBL14694259 | 0.74 | CYP1A2 (0.52) | MEN1KMT2AELANEALDH1A1GAA | |
| SCHEMBL10488230 | 0.74 | PADI4 (0.42) | MEN1KMT2AERN1ELANEALDH1A1 | |
| SCHEMBL985197 | 0.73 | ERN1 (0.46) | MEN1KMT2AERN1ALDH1A1GAA | |
| SCHEMBL39718 | 0.71 | ALDH1A1 (0.50) | MEN1KMT2AERN1ALDH1A1GAA | |
| SCHEMBL29392367 | 0.71 | ALDH1A1 (0.50) | MEN1KMT2AERN1ALDH1A1GAA | |
| SCHEMBL5749236 | 0.71 | TDP1 (0.41) | MEN1KMT2AERN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719049-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |