Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687755 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10692932 | 0.89 | GAA (0.48) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL6459389 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10693829 | 0.85 | TSHR (0.46) | MAPTSMN1; SMN2GAATP53ALOX15 | |
| SCHEMBL10644690 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10691180 | 0.80 | GAA (0.55) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL27561619 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL11124612 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL10691846 | 0.79 | KDM4E (0.35) | ALDH1A1KDM4ENPC1MAPTGAA | |
| SCHEMBL11044864 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4ENPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106512-B1 | HERBICIDAL ORTHO-ALKYL- AND ORTHO-ALKENYL-SUBSTITUTED BENZENESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-18 | — | — | EP | claimed |
| US-4678502-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-07 | — | — | US | claimed |
| EP-0106512-A2 | Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-25 | — | — | EP | claimed |
| US-4770690-A | Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0106512-B1 | HERBICIDAL ORTHO-ALKYL- AND ORTHO-ALKENYL-SUBSTITUTED BENZENESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-18 | — | — | EP | disclosed |
| US-4699650-A | Herbicidal ortho-alkyl-and ortho-alkenyl substituted benzenesulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| US-4678502-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0106512-A2 | Herbicidal ortho-alkyl- and ortho-alkenyl-substituted benzenesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |