Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.73 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107000 | 0.88 | MAPK1 (0.62) | KDM4EGLAHCAR3VCAM1MAPK1 | |
| SCHEMBL2772069 | 0.84 | HCAR3 (1.00) | KDM4EGLAHCAR3MAPK1ALDH1A1 | |
| SCHEMBL11448393 | 0.84 | MEN1 (0.58) | KDM4EGLAHCAR3VCAM1MAPK1 | |
| Hydrochloric Acid SCHEMBL18339287 | 0.83 | HCAR3 (0.97) | KDM4EGLAHCAR3MAPK1ALDH1A1 | |
| Acetic Acid Methyl Ester SCHEMBL27666636 | 0.81 | MAPK1 (0.54) | KDM4EGLAHCAR3VCAM1MAPK1 | |
| SCHEMBL11447915 | 0.81 | HCAR3 (0.55) | KDM4EGLAHCAR3VCAM1MAPK1 | |
| SCHEMBL11449805 | 0.81 | HCAR3 (0.55) | KDM4EGLAHCAR3VCAM1MAPK1 | |
| SCHEMBL11014183 | 0.81 | MAPK1 (0.73) | KDM4EGLAHCAR3VCAM1MAPK1 | |
| SCHEMBL27553444 | 0.80 | AKR1C3 (0.57) | KDM4EGLAHCAR3VCAM1MAPK1 | |
| SCHEMBL11447972 | 0.80 | HCAR3 (0.63) | KDM4EGLAHCAR3VCAM1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783472-A | 1H,3H-pyrrol[1,2-c]thiazole derivatives and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1988-11-08 | — | — | US | disclosed |