Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.73 |
| ▸ | CASP6 | P55212 | 1/20 | 0.68 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985417 | 0.91 | CASP6 (0.74) | MAPK1VCAM1CASP6TDP1HCAR3 | |
| Benzophenone SCHEMBL27290369 | 0.87 | MAPK1 (0.64) | MAPK1VCAM1CASP6CES2CES1 | |
| SCHEMBL5595136 | 0.86 | MAPK1 (0.69) | MAPK1VCAM1CASP6CES2CES1 | |
| SCHEMBL867944 | 0.86 | VCAM1 (0.69) | MAPK1VCAM1CASP6CES2CES1 | |
| SCHEMBL4609541 | 0.85 | VCAM1 (0.77) | MAPK1VCAM1CASP6CES2CES1 | |
| SCHEMBL8408501 | 0.85 | CES2 (0.77) | MAPK1VCAM1CES2CES1TDP1 | |
| SCHEMBL6561918 | 0.85 | VCAM1 (0.68) | MAPK1VCAM1CASP6CES2CES1 | |
| SCHEMBL5981573 | 0.85 | TSHR (0.71) | MAPK1VCAM1CES2CES1TDP1 | |
| SCHEMBL10903666 | 0.85 | MAPK1 (0.68) | MAPK1VCAM1CASP6CES2CES1 | |
| SCHEMBL333018 | 0.85 | VCAM1 (1.00) | MAPK1VCAM1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492708-A | Antiviral benzimidazoles | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | disclosed |