SCHEMBL2772069

SCHEMBL2772069

CN(C)c1ccc(C(=O)O)cc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 10/20 1.00
KDM4E B2RXH2 2/20 0.70
GLA P06280 1/20 0.70
CASP6 P55212 1/20 0.64
TSHR P16473 2/20 0.63
LMNA P02545 2/20 0.58
ALDH1A1 P00352 4/20 0.56
MAPT P10636 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
HPGD P15428 1/20 0.56
MAPK1 P28482 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NPSR1 Q6W5P4 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL18339287 0.98 HCAR3 (0.97) HCAR3KDM4EGLACASP6TSHR
SCHEMBL5326555 0.87 HCAR3 (0.77) HCAR3KDM4EGLACASP6TSHR
SCHEMBL11697178 0.85 HCAR3 (0.74) HCAR3KDM4EGLACASP6TSHR
SCHEMBL30503507 0.85 HCAR3 (0.74) HCAR3KDM4EGLALMNAALDH1A1
SCHEMBL10692442 0.84 KDM4E (0.76) HCAR3KDM4EGLALMNAALDH1A1
SCHEMBL1110902 0.83 HCAR3 (0.70) HCAR3KDM4EGLALMNAALDH1A1
SCHEMBL10502222 0.83 HCAR3 (1.00) HCAR3KDM4EGLACASP6TSHR
SCHEMBL9632337 0.81 HCAR3 (0.68) HCAR3KDM4EGLACASP6TSHR
SCHEMBL4299481 0.81 HCAR3 (0.68) HCAR3KDM4EGLALMNAALDH1A1
SCHEMBL4435755 0.80 HCAR3 (0.67) HCAR3KDM4EGLALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates AMBRX, INC. (US) 2026-03-10 US disclosed
CN-119455004-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-119455003-A Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2025-02-18 CN disclosed
CN-113660957-B Compositions, methods and uses comprising antibody-TLR agonist conjugates AMBRX公司 2024-12-13 CN disclosed
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20230359119-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-09 US disclosed
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 US disclosed
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 US disclosed
US-20230305393-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
US-20230305394-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
WO-2009043889-A2 OXADIAZOLE DERIVATIVES MERCK SERONO S.A. (CH) 2009-04-09 WO disclosed
WO-2009043889-A2 OXADIAZOLE DERIVATIVES MERCK SERONO S.A. (CH) 2009-04-09 WO disclosed
CN-101235244-A Dazzling-proof hard coating material and high hardness hard coating film using same DONGWOO FINE CHEM CO LTD (KR) 2008-08-06 CN disclosed
EP-0685470-B1 Benzene derivatives and pharmaceutical composition KUREHA CHEMICAL IND CO LTD (JP) 2002-09-11 EP disclosed
EP-0807628-B1 Aromatic compound and pharmaceutical composition KUREHA CHEMICAL IND CO LTD (JP) 2000-12-20 EP disclosed
EP-0807628-A1 Aromatic compound and pharmaceutical composition Kureha Chemical Industry Co., Ltd. (JP) 1997-11-19 EP disclosed
EP-0685470-A2 Benzene derivatives and pharmaceutical composition Kureha Chemical Industry Co., Ltd. (JP) 1995-12-06 EP disclosed
EP-0170069-B1 HAIR-DYEING COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1989-10-11 EP disclosed
US-4619666-A Hair dyes containing amino-nitrobenzoic acid or amino-nitrobenzene sulfonic acids as substantive dyes HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-10-28 US disclosed
EP-0170069-A1 Hair-dyeing compositions Henkel Kommanditgesellschaft auf Aktien (DE) 1986-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF TLR3, TLR1, TLR9 HCAR3 69/4885KDM4E 3476/4885GLA 3363/4885
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates TLR3, TLR2, TLR1 HCAR3 296/4885KDM4E 125/4885GLA 4009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.