SCHEMBL10692522

SCHEMBL10692522

Nc1ccc(S(=O)(=O)NCCOS(=O)(=O)O)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
CA12 O43570 2/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
KMT2A Q03164 2/20 0.41
CYP2D6 P10635 1/20 0.41
ALDH1A1 P00352 6/20 0.41
PKM P14618 4/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.41
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR6 P50406 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6885235 0.83 CA2 (0.53) CA1CA2CA9CA12CA4
SCHEMBL8761140 0.81 MAPT (0.46) CA1CA2KMT2ACYP2D6ALDH1A1
SCHEMBL8761433 0.80 CYP2D6 (0.64) CA1CA2CA9CA12CA4
SCHEMBL11306720 0.78 PRMT1 (0.58) CA1CA2CA9CA12CA4
SCHEMBL10693649 0.75 CA2 (0.42) CA1CA2CA9CA12CA14
SCHEMBL13892211 0.74 ALDH1A1 (0.71) CA2CA9CA12KMT2AALDH1A1
SCHEMBL13892215 0.72 HTT (0.47) KMT2AALDH1A1PKMMEN1POLB
SCHEMBL8707661 0.71 CA2 (0.40) CA1CA2CA9CA12CA4
SCHEMBL28836851 0.70 PKM (0.65) CA1CA2CA9CA12CA4
SCHEMBL3434572 0.70 CA2 (0.70) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed