Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096860 | 0.83 | L3MBTL1 (0.50) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL9538605 | 0.81 | IDO1 (0.34) | L3MBTL1MAPTNPSR1KDM4ENFE2L2 | |
| SCHEMBL10370964 | 0.81 | IDO1 (0.34) | L3MBTL1MAPTNPSR1NFE2L2TSHR | |
| SCHEMBL3391113 | 0.81 | L3MBTL1 (0.48) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL1253668 | 0.78 | ALDH1A1 (0.48) | KDM4ENISCHTSHRADRA2AADRA2B | |
| SCHEMBL28522552 | 0.78 | L3MBTL1 (0.46) | L3MBTL1MAPTNPSR1HPGDATM | |
| SCHEMBL5491774 | 0.77 | THRA (0.56) | — | |
| SCHEMBL11129111 | 0.77 | THRA (0.56) | — | |
| SCHEMBL18139176 | 0.77 | THRA (0.56) | — | |
| SCHEMBL11323416 | 0.77 | THRA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273426-A2 | Enamine derivatives, production thereof and electrophotographic plates containing the same | Hitachi Chemical Co., Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |