SCHEMBL10692626

SCHEMBL10692626

CC(c1cccc(C(C)(C)C)c1)c1ccc(O)c(C(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.47
HSD17B10 Q99714 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 4/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
GRM1 Q13255 1/20 0.47
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
PTPN5 P54829 1/20 0.42
AGO2 Q9UKV8 1/20 0.42
P2RX1 P51575 1/20 0.42
NOTUM Q6P988 1/20 0.42
POLB P06746 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9253648 0.89 ALDH1A1 (0.44) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL8424492 0.84 ACMSD (0.42) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL658651 0.84 KDM4E (0.56) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL1373696 0.84 KDM4E (0.56) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL2833452 0.83 KDM4E (0.62) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL11773172 0.83 ACMSD (0.41) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL11755689 0.82 CA1 (0.53) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL5964731 0.82 KDM4E (0.54) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL5697821 0.81 CSNK2A1 (0.57) KDM4EHSD17B10ALDH1A1HPGDMEN1
SCHEMBL5884677 0.80 ACMSD (0.62) KDM4EHSD17B10ALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262810-A2 Sheet recording material containing dye-forming components Fuji Photo Film Co., Ltd. (JP) 1988-04-06 EP disclosed