Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428483 | 0.93 | CA1 (0.58) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL658651 | 0.93 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL1373696 | 0.93 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL5964731 | 0.91 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL8424356 | 0.91 | CSNK2A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL8423890 | 0.90 | HPGD (0.53) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL27396609 | 0.88 | ACMSD (0.65) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL11755689 | 0.88 | CA1 (0.53) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL1649282 | 0.88 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL5697821 | 0.87 | CSNK2A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562242-A | Branched polycarbonate from carboxy containing diphenol | GENERAL ELECTRIC COMPANY (US) | 1985-12-31 | — | — | US | claimed |
| EP-1210090-B1 | USE OF CHEMICAL CHELATORS AS REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | MERCK SHARP & DOHME (NL) | 2014-06-18 | — | — | EP | disclosed |
| US-20100075938-A1 | Use of Chemical Chelators as Reversal Agents for Drug-Induced Neuromuscular Block | N.V. ORGANON | 2010-03-25 | — | — | US | disclosed |
| US-20070299035-A1 | USE OF CHEMICAL CHELATORS AS REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | N.V. ORGANON (NL) | 2007-12-27 | — | — | US | disclosed |
| US-7265099-B1 | Use of chemical chelators as reversal agents for drug-induced neuromuscular block | ORGANON N.V. (NL) | 2007-09-04 | — | — | US | disclosed |
| EP-1210090-A2 | USE OF CHEMICAL CHELATORS AS REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | Akzo Nobel N.V. (NL) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012202-A2 | USE OF CHEMICAL CHELATORS AS REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | AKZO NOBEL N.V. (NL) | 2001-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299035-A1 | USE OF CHEMICAL CHELATORS AS REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | ACHE, NMBR, KCNMB1 | KDM4E 184/4885ALDH1A1 1411/4885HPGD 2927/4885 |
| US-20100075938-A1 | Use of Chemical Chelators as Reversal Agents for Drug-Induced Neuromuscular Block | ACHE, BCHE, KCNMB1 | KDM4E 81/4885ALDH1A1 1954/4885HPGD 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.