Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.64 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | TYMP | P19971 | 1/20 | 0.58 |
| ▸ | TYMS | P04818 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692633 | 1.00 | TK1 (0.64) | TK1BCHETYMPTYMSCYP1A2 | |
| SCHEMBL5702260 | 1.00 | TK1 (0.64) | TK1BCHETYMPTYMSCYP1A2 | |
| SCHEMBL6294757 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS | |
| SCHEMBL6294759 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS | |
| SCHEMBL15235291 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS | |
| SCHEMBL17123679 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS | |
| SCHEMBL7541144 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS | |
| SCHEMBL13255800 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS | |
| SCHEMBL21133906 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS | |
| SCHEMBL3599668 | 0.93 | TYMS (0.56) | TK1BCHETYMPTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252989-A1 | 2'-DEOXY-5-TRIFLUOROMETHYLURIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1988-01-20 | — | — | EP | disclosed |