Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 5/20 | 0.56 |
| ▸ | TK1 | P04183 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | TYMP | P19971 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133906 | 1.00 | TYMS (0.56) | TYMSTK1BCHETYMP | |
| SCHEMBL6294757 | 1.00 | TYMS (0.56) | TYMSTK1BCHETYMP | |
| SCHEMBL3599668 | 1.00 | TYMS (0.56) | TYMSTK1BCHETYMP | |
| SCHEMBL15235291 | 1.00 | TYMS (0.56) | TYMSTK1BCHETYMP | |
| SCHEMBL17123679 | 1.00 | TYMS (0.56) | TYMSTK1BCHETYMP | |
| SCHEMBL6294759 | 1.00 | TYMS (0.56) | TYMSTK1BCHETYMP | |
| SCHEMBL13255800 | 1.00 | TYMS (0.56) | TYMSTK1BCHETYMP | |
| Idoxuridine SCHEMBL8694067 | 0.97 | TK1 (0.62) | TYMSTK1BCHETYMP | |
| SCHEMBL5702260 | 0.93 | TK1 (0.64) | TYMSTK1BCHETYMP | |
| SCHEMBL10692639 | 0.93 | TK1 (0.64) | TYMSTK1BCHETYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344047-B2 | Oligonucleotide ligation | ATDBIO LTD. (GB) | 2019-07-09 | — | — | US | disclosed |
| US-9285319-B2 | Nucleic acid base analogs with quenching and fluorescent activities and applications thereof | RIKEN (JP) | 2016-03-15 | — | — | US | disclosed |
| US-20130231473-A1 | OLIGONUCLEOTIDE LIGATION | ATDBIO LTD. (GB) | 2013-09-05 | — | — | US | disclosed |
| US-20130122506-A1 | NUCLEIC ACID BASE ANALOGS WITH QUENCHING AND FLUORESCENT ACTIVITIES AND APPLICATIONS THEREOF | TAGCYX BIOTECHNOLOGIES C/O RIKEN (JP) | 2013-05-16 | — | — | US | disclosed |
| EP-2562255-A1 | NUCLEIC ACID BASE ANALOG WITH QUENCHING CHARACTERISTICS AND FLUORESCENCE AND APPLICATION THEREOF | Riken (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-20020177695-A1 | Nucleic acid probes and methods | DUKE UNIVERSITY | 2002-11-28 | — | — | US | disclosed |
| US-6288221-B1 | REPLACING NUCLEOSIDE WITH DIMETHOXYTRITYL, PHOSPHORAMIDITE, OR HALONUCLEOSIDE DERIVATIVE; ELECTROCHEMICAL OR PHOTOCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES | DUKE UNIVERSITY | 2001-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344047-B2 | Oligonucleotide ligation | LIG1, LIG3, LIG4 | TYMS 116/4885TK1 44/4885BCHE 3249/4885 |
| US-20020177695-A1 | Nucleic acid probes and methods | NUDT1, NT5C3B, NT5C2 | TYMS 52/4885TK1 71/4885BCHE 3856/4885 |
| US-20130231473-A1 | OLIGONUCLEOTIDE LIGATION | LIG3, LIG1, LIG4 | TYMS 113/4885TK1 79/4885BCHE 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.