Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693713 | 0.80 | MAP3K14 (0.39) | PARP1 | |
| SCHEMBL31492697 | 0.74 | GAA (0.33) | TDP2NSD2HSP90AA1PAX8 | |
| SCHEMBL30613493 | 0.68 | PARP1 (0.42) | PARP1 | |
| SCHEMBL6493919 | 0.68 | PARP1 (0.42) | PARP1 | |
| SCHEMBL11127247 | 0.67 | MAOA (0.41) | — | |
| SCHEMBL791712 | 0.62 | — | — | |
| SCHEMBL3238451 | 0.62 | PGR (0.31) | PARP1 | |
| SCHEMBL9718443 | 0.62 | POLB (0.31) | — | |
| SCHEMBL23374860 | 0.60 | ACHE (0.36) | — | |
| SCHEMBL15730214 | 0.59 | KDM4E (0.43) | TDP2NSD2HSP90AA1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |