Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 3/20 | 0.57 |
| ▸ | BACE1 | P56817 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD1 | P21728 | 3/20 | 0.54 |
| ▸ | DRD5 | P21918 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10623445 | 0.95 | ALDH1A1 (0.64) | METAP1MAOAKDM4EALDH1A1MAPT | |
| SCHEMBL29633762 | 0.91 | DRD1 (0.58) | METAP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2914928 | 0.91 | DRD1 (0.58) | METAP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL23835146 | 0.91 | METAP1 (0.73) | METAP1MAOAKDM4EALDH1A1MAPT | |
| SCHEMBL30887372 | 0.91 | METAP1 (0.73) | METAP1MAOAKDM4EALDH1A1MAPT | |
| SCHEMBL25499549 | 0.89 | METAP1 (0.70) | METAP1MAOAKDM4EALDH1A1MAPT | |
| SCHEMBL3759572 | 0.86 | MAPK14 (0.64) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7040518 | 0.85 | DRD1 (0.57) | METAP1MAOAKDM4EALDH1A1MAPT | |
| SCHEMBL6642979 | 0.85 | DRD1 (0.57) | METAP1MAOAKDM4EALDH1A1MAPT | |
| SCHEMBL5337855 | 0.85 | MAPK14 (0.67) | METAP1MAOAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |