Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693467 | 0.86 | ABCB1 (0.55) | ABCB1ABCG2ALDH1A1KMT2APOLB | |
| SCHEMBL6380841 | 0.86 | ABCB1 (0.57) | ABCB1ABCG2ALDH1A1KMT2APOLB | |
| SCHEMBL10693447 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2ABCB1ALDH1A1HSD17B10KMT2A | |
| SCHEMBL10692445 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2ABCB1ALDH1A1HSD17B10KMT2A | |
| SCHEMBL10693200 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL28676656 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL10693527 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL10694565 | 0.76 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1HSD17B10KMT2APOLB | |
| SCHEMBL10693834 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10KMT2A | |
| SCHEMBL10689558 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |