Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796358 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10693603 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10692445 | 0.84 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL14818749 | 0.83 | TSHR (0.68) | ALDH1A1HSD17B10MAPTHDAC3HDAC4 | |
| SCHEMBL10693582 | 0.83 | TDP1 (0.61) | SMN1; SMN2ALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL10693438 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL28756536 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1HSD17B10MAPTHDAC3 | |
| SCHEMBL10991297 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10692647 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10689558 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |