Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380841 | 0.87 | ABCB1 (0.57) | ABCB1ABCG2KMT2APOLBGAA | |
| SCHEMBL10692685 | 0.86 | SMN1; SMN2 (0.57) | ABCB1ABCG2KMT2APOLBGAA | |
| SCHEMBL10692720 | 0.83 | GAA (0.57) | ABCB1KMT2APOLBGAAMEN1 | |
| SCHEMBL10690219 | 0.78 | ALDH1A1 (0.59) | ABCB1KMT2APOLBGAAMEN1 | |
| SCHEMBL31123664 | 0.76 | GAA (0.57) | ABCB1ABCG2KMT2APOLBGAA | |
| SCHEMBL6101314 | 0.76 | KMT2A (0.55) | KMT2APOLBGAAMEN1LMNA | |
| SCHEMBL8804509 | 0.76 | MEN1 (0.52) | KMT2APOLBGAAMEN1LMNA | |
| SCHEMBL13352155 | 0.76 | ALDH1A1 (0.71) | KMT2APOLBGAAMEN1LMNA | |
| SCHEMBL10483445 | 0.75 | MAPT (0.48) | ABCB1ABCG2KMT2APOLBMEN1 | |
| SCHEMBL8637193 | 0.75 | KMT2A (0.60) | KMT2AGAAMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |