Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693447 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL7796358 | 0.88 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10692647 | 0.87 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10691781 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL10689596 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL10690936 | 0.84 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL28220176 | 0.84 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1GAAKMT2ARAB9A | |
| SCHEMBL4681910 | 0.81 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL10694565 | 0.80 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL10694549 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |