Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779200 | 0.92 | AR (0.47) | ARALPLDRD2ICMT | |
| SCHEMBL9798963 | 0.83 | DRD2 (0.34) | DRD2CA12CA1CA9 | |
| SCHEMBL1070648 | 0.82 | AR (0.44) | ARTRPV4ICMTCYP19A1CYP2A6 | |
| SCHEMBL9801074 | 0.81 | DRD2 (0.33) | DRD2CA12CA1CA9 | |
| Bromide SCHEMBL9800983 | 0.80 | DRD2 (0.33) | DRD2CA12CA1CA9 | |
| SCHEMBL25385957 | 0.78 | CYP11B2 (0.35) | ARTRPV4ALDH1A1 | |
| SCHEMBL30574837 | 0.78 | CYP11B2 (0.35) | ARTRPV4ALDH1A1 | |
| SCHEMBL1067888 | 0.77 | PREP (0.43) | KIF11CYP19A1CA12CA1CA9 | |
| SCHEMBL8667470 | 0.76 | DRD2 (0.37) | ARDRD2CA12CA1CA9 | |
| SCHEMBL23042779 | 0.76 | DRD2 (0.42) | ARDRD2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946355-B2 | Hydroxyaryl functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2015-02-03 | — | — | US | disclosed |
| EP-2448984-B1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2014-03-12 | — | — | EP | disclosed |
| US-20120136113-A1 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| EP-2448984-A2 | HYDROXYARYL FUNCTIONALIZED POLYMERS | Bridgestone Corporation (JP) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011002930-A2 | HYDROXYARYL FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2011-01-06 | — | — | WO | disclosed |