Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9800983 | 0.98 | DRD2 (0.33) | DRD2CA12CA1CA9 | |
| SCHEMBL9798963 | 0.98 | DRD2 (0.34) | DRD2CA12CA1CA9GABRA1 | |
| SCHEMBL23042779 | 0.90 | DRD2 (0.42) | DRD2CA12CA1CA9 | |
| SCHEMBL27398878 | 0.90 | DRD2 (0.37) | DRD2CA12CA1CA9 | |
| SCHEMBL1069272 | 0.81 | AR (0.40) | DRD2CA12CA1CA9 | |
| SCHEMBL9051730 | 0.75 | PREP (0.43) | CA12CA1CA9GABRA1GABRG2 | |
| SCHEMBL1779200 | 0.74 | AR (0.47) | DRD2 | |
| SCHEMBL8667470 | 0.74 | DRD2 (0.37) | DRD2CA12CA1CA9 | |
| SCHEMBL10423548 | 0.73 | NPSR1 (0.38) | DRD2 | |
| SCHEMBL1396396 | 0.73 | CA12 (0.41) | CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008471-A | Process for the preparation of rooperol | ROOPEROL (N.A.) (NL) | 1991-04-16 | — | — | US | disclosed |