Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690950 | 0.89 | HTR1B (0.50) | HTR1BKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL10692959 | 0.87 | HTR1B (0.56) | HTR1BKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL10695350 | 0.87 | ALDH1A1 (0.41) | HTR1BKDM4ECYP1A2ALDH1A1HPGD | |
| SCHEMBL10691295 | 0.86 | HTR1B (0.60) | HTR1BKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL10692799 | 0.86 | HTR1B (0.60) | HTR1BKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL10691756 | 0.86 | HTR1B (0.60) | HTR1BKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL27603617 | 0.85 | CNR1 (0.41) | HTR1BKDM4ECYP1A2ALDH1A1HPGD | |
| SCHEMBL10695962 | 0.85 | HTR1B (0.62) | HTR1BKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL10693274 | 0.84 | HTR1B (0.47) | HTR1BKDM4ECYP1A2ALDH1A1SCN1A | |
| SCHEMBL3694800 | 0.84 | ALDH1A1 (0.41) | HTR1BKDM4ECYP1A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |