Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693307 | 0.91 | HTR1B (0.50) | HTR2AHTR1BMAOAMAOBTERT | |
| SCHEMBL10691295 | 0.88 | HTR1B (0.60) | HTR1BSIGMAR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL10691756 | 0.88 | HTR1B (0.60) | HTR1BSIGMAR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL10692799 | 0.88 | HTR1B (0.60) | HTR1BSIGMAR1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL10692825 | 0.88 | MAOB (0.46) | HTR2AMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL10695962 | 0.87 | HTR1B (0.62) | HTR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10693321 | 0.86 | CYP1A2 (0.44) | HTR2AKDM4EALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL10688770 | 0.85 | CYP1A2 (0.42) | HTR1BSIGMAR1CYP1A2CYP2A6 | |
| SCHEMBL10694848 | 0.82 | HTR1B (0.61) | HTR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10690312 | 0.82 | HTR1B (0.51) | HTR1BKDM4ESLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792551-A | 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0132351-A2 | 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-01-30 | — | — | EP | disclosed |